{"id":539356,"date":"2026-10-30T16:10:46","date_gmt":"2026-10-30T08:10:46","guid":{"rendered":"https:\/\/ww.xysww.com\/?p=539356"},"modified":"2026-10-30T16:10:46","modified_gmt":"2026-10-30T08:10:46","slug":"%e7%a6%8f%e4%bb%96%e6%9b%bf%e5%b0%bcfostamatinib%e4%be%9b%e5%ba%94%e5%95%86%e5%ae%9e%e5%8a%9b%e4%b8%8e%e7%94%a8%e6%88%b7%e5%8f%a3%e7%a2%91%e6%b7%b1%e5%ba%a6%e8%a7%a3%e6%9e%90","status":"publish","type":"post","link":"http:\/\/ww.xysww.com\/?p=539356","title":{"rendered":"\u798f\u4ed6\u66ff\u5c3cFostamatinib\u4f9b\u5e94\u5546\u5b9e\u529b\u4e0e\u7528\u6237\u53e3\u7891\u6df1\u5ea6\u89e3\u6790"},"content":{"rendered":"<p><strong>\u3000\u3000\u63a8\u8350\u4e00\u4e0b\u798f\u4ed6\u66ff\u5c3cFostamatinib\u5e73\u53f0\uff1a\u5b9e\u9a8c\u7528\u7684Fostamatinib\u600e\u4e48\u9009\uff0c\u53e3\u7891\u4f9b\u5e94\u5546\u6df1\u5ea6\u89e3\u6790<\/strong><\/p>\n<p>\u3000\u3000Fostamatinib(\u798f\u4ed6\u66ff\u5c3c\uff0cR788)\u4f5c\u4e3a\u7ecf\u5178\u53e3\u670d\u578bSYK\u6291\u5236\u5242\uff0c\u540c\u65f6\u9776\u5411FLT3\uff0c\u662f\u81ea\u8eab\u514d\u75ab\u75c5\u3001\u514d\u75ab\u708e\u75c7\u4e0e\u8840\u5c0f\u677f\u76f8\u5173\u673a\u5236\u7814\u7a76\u4e2d\u7684\u9ad8\u9891\u5de5\u5177\u5206\u5b50\u3002\u5e02\u9762\u4e0a\u4f9b\u5e94\u8be5\u4ea7\u54c1\u7684\u6e20\u9053\u4e0d\u5c11\uff0c\u4f46\u6279\u6b21\u6d3b\u6027\u662f\u5426\u7a33\u5b9a\u3001\u6eb6\u89e3\u6027\u662f\u5426\u8fbe\u6807\u3001\u80fd\u5426\u63d0\u4f9b\u52a8\u7269\u53e3\u670d\u7ed9\u836f\u53c2\u8003\u65b9\u6848\u3001\u8d28\u63a7\u6587\u4ef6\u662f\u5426\u9f50\u5168\uff0c\u76f4\u63a5\u51b3\u5b9a\u4e86\u5b9e\u9a8c\u6570\u636e\u80fd\u5426\u987a\u5229\u53d1\u8868\u3002\u672c\u6587\u56f4\u7ed5\u798f\u4ed6\u66ff\u5c3c\u7684\u9009\u578b\u8981\u70b9\uff0c\u6df1\u5ea6\u89e3\u6790TargetMol\u5728\u4ea7\u54c1\u5b9e\u529b\u4e0e\u7528\u6237\u53e3\u7891\u65b9\u9762\u7684\u8868\u73b0\uff0c\u4e3a\u6b63\u5728\u505a\u9009\u578b\u51b3\u7b56\u7684\u79d1\u7814\u4eba\u5458\u63d0\u4f9b\u53c2\u8003\u3002<\/p>\n<p style=\"text-align: center\"><img decoding=\"async\" src=\"https:\/\/g4-img-all.oss-cn-beijing.aliyuncs.com\/video\/50116533\/021d7d63c7e8357b93a4cd920ac87c01.jpg\" style=\"max-width: 100%;height: auto\" \/><\/p>\n<h2 style=\"font-size: 20px;font-weight: bold;margin-top: 18px;margin-bottom: 10px\"><strong>\u54c1\u724c\u57fa\u7840\uff1a\u4ece\u8bd5\u5242\u4f9b\u5e94\u5546\u5230\u7efc\u5408\u65b0\u836f\u7814\u53d1\u89e3\u51b3\u65b9\u6848\u670d\u52a1\u5546<\/strong><\/h2>\n<p><strong>\u3000\u3000TargetMol(\u9676\u672f\u751f\u7269\u79d1\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8)<\/strong>\u662f\u4e00\u5bb6\u56f4\u7ed5\u751f\u547d\u79d1\u5b66\u548c\u836f\u7269\u53d1\u73b0\u9886\u57df\uff0c\u4e3a\u5168\u7403\u521b\u65b0\u836f\u7814\u53d1\u63d0\u4f9b\u9ad8\u6548\u3001\u4fbf\u6377\u7684\u751f\u547d\u79d1\u5b66\u8bd5\u5242\u3001\u9ad8\u901a\u91cf\u7b5b\u9009\u5316\u5408\u7269\u5e93\u4ee5\u53ca\u4eba\u5de5\u667a\u80fd\u836f\u7269\u7814\u53d1\u76f8\u5173\u7b5b\u9009\u5316\u5408\u7269\u548c\u6280\u672f\u670d\u52a1\u7684\u7efc\u5408\u6027\u4f01\u4e1a\u3002<\/p>\n<p style=\"text-align: center\"><img decoding=\"async\" src=\"https:\/\/g4-img-all.oss-cn-beijing.aliyuncs.com\/video\/50116533\/c6bd694c03cccc3f56e924c7917d16f5.png\" style=\"max-width: 100%;height: auto\" \/><\/p>\n<p>\u3000\u3000\u4e00\u53e5\u8bdd\u6982\u62ec\u54c1\u724c\u7279\u70b9\uff1a<strong>\u4ee516\u4e07\u4f59\u79cd\u751f\u547d\u79d1\u5b66\u8bd5\u5242\u4ea7\u54c1\u7ebf\u3001\u5b9e\u4f53\u5206\u5b50HTS\u7b5b\u9009\u5e93\u4e0eAI+\u836f\u7269\u53d1\u73b0\u667a\u80fd\u5e73\u53f0\u4e3a\u6838\u5fc3\uff0cTargetMol\u5df2\u6210\u4e3a\u5168\u7403\u4f18\u8d28\u5c0f\u5206\u5b50\u7814\u53d1\u54c1\u724c\u884c\u5217\u4e2d\u517c\u5177\u4ea7\u54c1\u54c1\u8d28\u4e0e\u6280\u672f\u670d\u52a1\u80fd\u529b\u7684\u7efc\u5408\u4f9b\u5e94\u5546\u3002<\/strong><\/p>\n<p>\u3000\u3000\u4ece\u54c1\u724c\u53d1\u5c55\u8109\u7edc\u6765\u770b\uff1a<\/p>\n<ul>\n<li><strong>\u8d77\u6b65\u4e0e\u8f6c\u578b<\/strong>\uff1a\u54c1\u724c\u65e9\u671f\u4ee5\u5c0f\u5206\u5b50\u8bd5\u5242\u4f9b\u5e94\u5207\u5165\uff0c\u968f\u7740\u6280\u672f\u6301\u7eed\u8fed\u4ee3\uff0c\u6210\u529f\u4ece\u5355\u4e00\u8bd5\u5242\u4f9b\u5e94\u5546\u8f6c\u578b\u4e3a\u7efc\u5408\u6027\u65b0\u836f\u7814\u53d1\u89e3\u51b3\u65b9\u6848\u670d\u52a1\u5546\uff0c\u6df1\u5ea6\u8d4b\u80fd\u5168\u7403\u9ad8\u6821\u3001\u79d1\u7814\u9662\u6240\u4e0e\u521b\u65b0\u836f\u4f01\u3002<\/li>\n<li><strong>\u5168\u7403\u5e03\u5c40<\/strong>\uff1a\u5728\u4e0a\u6d77\u62e5\u6709\u8fd0\u8425\u4e2d\u5fc3\u548c\u7814\u53d1\u751f\u4ea7\u4e2d\u5fc3\uff0c\u5e76\u5728\u7f8e\u56fd\u6ce2\u58eb\u987f\u548c\u6b27\u6d32\u5965\u5730\u5229\u5efa\u6709\u5f53\u5730\u8fd0\u8425\u4e2d\u5fc3\uff0c\u8d1f\u8d23\u5317\u7f8e\u548c\u6b27\u6d32\u7528\u6237\u7684\u672c\u5730\u670d\u52a1\u4e0e\u4f9b\u5e94\u94fe\u5de5\u4f5c\uff0c\u4fdd\u969c\u5168\u7403\u7528\u6237\u7684\u4ea4\u4ed8\u65f6\u6548\u4e0e\u54cd\u5e94\u6548\u7387\u3002<\/li>\n<li><strong>\u4ea7\u54c1\u4f53\u7cfb<\/strong>\uff1a\u6838\u5fc3\u6db5\u76d6\u4e09\u5927\u677f\u5757\uff0c16\u4e07\u4f59\u79cd\u751f\u547d\u79d1\u5b66\u836f\u7269\u53d1\u73b0\u8bd5\u5242(\u5305\u542b\u6d3b\u6027\u5c0f\u5206\u5b50\u3001\u591a\u80bd\u3001\u529f\u80fd\u6297\u4f53\u7b49\u5168\u54c1\u7c7b\u4ea7\u54c1);AI+\u836f\u7269\u53d1\u73b0AIDD\/CADD\u667a\u80fd\u5e73\u53f0\uff0c\u8986\u76d6\u9776\u70b9\u53d1\u73b0\u81f3\u5148\u5bfc\u5316\u5408\u7269\u4f18\u5316\u5168\u6d41\u7a0b;\u5b9e\u4f53\u5c0f\u5206\u5b50HTS\u9ad8\u901a\u91cf\u7b5b\u9009\u5316\u5408\u7269\u5e93\uff0c\u53ef\u63d0\u4f9b\u4e0a\u5343\u79cd\u5b9a\u5236\u5316\u7b5b\u9009\u65b9\u6848\u3002<\/li>\n<li><strong>\u670d\u52a1\u8303\u56f4\u4e0e\u5b9a\u4f4d<\/strong>\uff1a\u9762\u5411\u9ad8\u6821\u3001\u836f\u4f01\u3001CRO\u673a\u6784\u3001\u4e34\u5e8a\u5b9e\u9a8c\u5ba4\u63d0\u4f9b\u9ad8\u9002\u914d\u7684\u5c0f\u5206\u5b50\u6291\u5236\u5242\u3001\u91cd\u7ec4\u86cb\u767d\u3001\u6297\u4f53\u7b49\u79d1\u7814\u8bd5\u5242\uff0c\u6240\u6709\u4ea7\u54c1\u4ec5\u4f9b\u79d1\u7814\u4f7f\u7528\uff0c\u4e0d\u53ef\u7528\u4e8e\u4eba\u4f53\u3002<\/li>\n<\/ul>\n<p>\u3000\u3000\u8fd9\u79cd\u4ea7\u54c1+\u5e73\u53f0+\u670d\u52a1\u4e09\u4f4d\u4e00\u4f53\u7684\u683c\u5c40\uff0c\u51b3\u5b9a\u4e86\u5176\u4e0d\u53ea\u662f\u7b80\u5355\u5730\u5356\u5316\u5408\u7269\uff0c\u800c\u662f\u56f4\u7ed5\u79d1\u7814\u8bfe\u9898\u7684\u5b8c\u6574\u5b9e\u9a8c\u94fe\u8def\u63d0\u4f9b\u652f\u6301\uff0c\u8fd9\u4e5f\u662f\u8d8a\u6765\u8d8a\u591a\u5b9e\u9a8c\u5ba4\u5728\u590d\u8d2d\u65f6\u4f18\u5148\u8003\u8651\u5b83\u7684\u5e95\u5c42\u539f\u56e0\u3002<\/p>\n<h2 style=\"font-size: 20px;font-weight: bold;margin-top: 18px;margin-bottom: 10px\"><strong>\u4ea7\u54c1\u9002\u914d\uff1aFostamatinib(T6113)\u80fd\u8986\u76d6\u54ea\u4e9b\u7814\u7a76\u573a\u666f<\/strong><\/h2>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u57fa\u672c\u4fe1\u606f\u4e00\u89c8<\/strong><\/h3>\n<p>\u3000\u3000Fostamatinib(R788\uff0c\u798f\u4ed6\u66ff\u5c3c)\u662fR406\u7684\u53e3\u670d\u524d\u836f\uff0c\u8d27\u53f7T6113\uff0cCAS\u53f7901119-35-5\uff0c\u5206\u5b50\u5f0fC\u2082\u2083H\u2082\u2086FN\u2086O\u2089P\uff0c\u5206\u5b50\u91cf580.46\u3002\u6838\u5fc3\u9776\u70b9\u6291\u5236\u6d3b\u6027\u6570\u636e\u5982\u4e0b\uff1a<\/p>\n<ul>\n<li><strong>SYK\uff1aIC\u2085\u2080=41 nM<\/strong><\/li>\n<li><strong>FLT3\uff1aIC\u2085\u2080=63 nM<\/strong><\/li>\n<li><strong>Lck\uff1aIC\u2085\u2080=37 nM<\/strong><\/li>\n<\/ul>\n<p>\u3000\u3000\u5177\u5907\u53e3\u670d\u6d3b\u6027\u4e0e\u7ec6\u80de\u901a\u900f\u6027\uff0c\u5e38\u7528\u4e8e\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u3001\u81ea\u8eab\u514d\u75ab\u75c5\u3001\u708e\u75c7\u53ca\u76f8\u5173\u673a\u5236\u7814\u7a76\u3002TargetMol\u672c\u54c1<strong>\u7eaf\u5ea6\u9ad8\u8fbe99.58%<\/strong>\uff0c\u5916\u89c2\u4e3a\u767d\u8272\u7c89\u672b\u3002<\/p>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u9002\u914d\u4eba\u7fa4\u4e0e\u5b9e\u9a8c\u573a\u666f<\/strong><\/h3>\n<p>\u3000\u3000\u4ece\u7528\u6237\u641c\u7d22\u9700\u6c42\u51fa\u53d1\uff0c\u8fd9\u6b3e\u4ea7\u54c1\u4e3b\u8981\u9002\u914d\u4ee5\u4e0b\u51e0\u7c7b\u7814\u7a76\u573a\u666f\uff1a<\/p>\n<ol>\n<li><strong>\u4f53\u5916\u6fc0\u9176\u5b9e\u9a8c<\/strong>\uff1aSYK\u3001FLT3\u7b49\u6fc0\u9176\u6d3b\u6027\u68c0\u6d4b\uff0c\u9a8c\u8bc1\u9776\u70b9\u6291\u5236\u6548\u529b\u3002<\/li>\n<li><strong>\u7ec6\u80de\u708e\u75c7\u6a21\u578b<\/strong>\uff1a\u514d\u75ab\u7ec6\u80de\u523a\u6fc0\u5b9e\u9a8c\uff0c\u63a2\u7a76SYK\u4ecb\u5bfc\u7684\u708e\u75c7\u4fe1\u53f7\u8c03\u63a7\u4e0e\u708e\u75c7\u56e0\u5b50\u91ca\u653e\u673a\u5236\u3002<\/li>\n<li><strong>\u4f53\u5185\u52a8\u7269\u7ed9\u836f\u7814\u7a76<\/strong>\uff1a\u81ea\u8eab\u514d\u75ab\u52a8\u7269\u6a21\u578b\u4e2d\uff0c\u8bc4\u4ef7\u53e3\u670d\u7ed9\u836f\u5bf9\u514d\u75ab\u5e94\u7b54\u3001\u8840\u5c0f\u677f\u6c34\u5e73\u7684\u8c03\u63a7\u6548\u679c\u3002\u4ea7\u54c1\u914d\u5957<strong>10% DMSO+40% PEG300+5% Tween80+45% Saline<\/strong>\u7684\u6210\u719f\u4f53\u5185\u7ed9\u836f\u914d\u65b9\uff0c\u65e0\u9700\u81ea\u884c\u6478\u7d22\u3002<\/li>\n<li><strong>\u4fe1\u53f7\u901a\u8def\u673a\u5236\u7814\u7a76<\/strong>\uff1aSYK\u4fe1\u53f7\u901a\u8def\u65b9\u5411\u8bfe\u9898\uff0c\u963b\u65adSYK\u4ecb\u5bfc\u7684\u4e0b\u6e38\u4fe1\u53f7\u6d3b\u5316\uff0c\u8c03\u63a7\u514d\u75ab\u7ec6\u80de\u6d3b\u5316\u3002<\/li>\n<\/ol>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u89c4\u683c\u4e0e\u5242\u578b\u9009\u62e9<\/strong><\/h3>\n<ul>\n<li><strong>\u56fa\u4f53\u7c89\u672b<\/strong>\uff1a\u8986\u76d61 mg\u30012 mg\u30015 mg\u300110 mg\u300125 mg\u300150 mg\u3001100 mg\u3001500 mg\u68af\u5ea6\u89c4\u683c\uff0c\u6309\u5b9e\u9a8c\u4f53\u91cf\u7075\u6d3b\u9009\u62e9\uff0c\u907f\u514d\u6d6a\u8d39\u3002<\/li>\n<li><strong>\u9884\u5236\u6bcd\u6db2<\/strong>\uff1a\u63d0\u4f9b1 mL \u00d7 10 mM DMSO\u9884\u5236\u6eb6\u6db2\uff0c\u89c4\u907f\u79f0\u91cf\u8bef\u5dee\uff0c\u7279\u522b\u9002\u5408\u9700\u8981\u5feb\u901f\u5f00\u5c55\u9884\u5b9e\u9a8c\u6216\u5bf9\u6d53\u5ea6\u51c6\u786e\u6027\u8981\u6c42\u9ad8\u7684\u5b9e\u9a8c\u3002<\/li>\n<\/ul>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u6eb6\u89e3\u6027\u4e0e\u4fdd\u5b58\u8fd0\u8f93\u6761\u4ef6<\/strong><\/h3>\n<ul>\n<li><strong>DMSO\u6eb6\u89e3\u5ea6\u53ef\u8fbe127.50 mg\/mL<\/strong>\uff0c\u6c34\u3001\u4e59\u9187\u4e2d\u96be\u6eb6\uff0c\u6eb6\u89e3\u6027\u80fd\u5728\u540c\u7c7bSYK\u6291\u5236\u5242\u4e2d\u8868\u73b0\u4f18\u5f02\u3002<\/li>\n<li>\u7c89\u672b\u9632\u6f6e\u3001-20\u2103\u6761\u4ef6\u4e0b\u7a33\u5b9a\u4fdd\u5b583\u5e74;\u914d\u5236\u6bcd\u6db2\u540e-80\u2103\u53ef\u4fdd\u5b581\u5e74;\u84dd\u51b0\u907f\u5149\u8fd0\u8f93\uff0c\u5168\u94fe\u6761\u4fdd\u969c\u6d3b\u6027\u7a33\u5b9a\u3002<\/li>\n<\/ul>\n<h2 style=\"font-size: 20px;font-weight: bold;margin-top: 18px;margin-bottom: 10px\"><strong>\u4e09\u5927\u6838\u5fc3\u4eae\u70b9<\/strong><\/h2>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u4eae\u70b9\u4e00\uff1a\u8d28\u63a7\u4f53\u7cfb\u5e26\u6765\u7684\u9776\u70b9\u6d3b\u6027\u7a33\u5b9a\u6027<\/strong><\/h3>\n<p>\u3000\u3000\u4ea7\u54c1\u7ecf<strong>LCMS\u3001HNMR\u591a\u91cd\u8d28\u63a7<\/strong>\uff0c\u6bcf\u6279\u6b21\u968f\u8d27\u9644\u5e26Datasheet\u3001SDS\u3001COA\u3001LCMS\u3001HNMR\u5168\u5957\u8d28\u63a7\u56fe\u8c31\u8d44\u6599\uff0c\u6ee1\u8db3\u8bba\u6587\u6295\u7a3f\u6eaf\u6e90\u9700\u6c42\u3002\u7eaf\u5ea699.58%\u3001\u6279\u6b21\u95f4\u6291\u5236\u6d3b\u6027\u7a33\u5b9a\uff0c\u76f4\u63a5\u89e3\u51b3\u5e02\u9762\u4e0a\u90e8\u5206\u4ea7\u54c1\u6fc0\u9176\u6d3b\u6027\u4e0d\u7a33\u5b9a\u3001\u6279\u6b21\u5dee\u5f02\u5927\u7684\u75db\u70b9\u3002<\/p>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u4eae\u70b9\u4e8c\uff1a\u6210\u719f\u7684\u5e94\u7528\u65b9\u6848\u652f\u6301<\/strong><\/h3>\n<p>\u3000\u3000\u6280\u672f\u56e2\u961f\u53ef\u63d0\u4f9b\u6fc0\u9176\u7b5b\u9009\u3001\u7ec6\u80de\u7ed9\u836f\u3001\u4f53\u5185\u9020\u6a21\u65b9\u6848\u53c2\u8003\uff0c\u914d\u5957\u6d53\u5ea6\u53c2\u8003\u65b9\u6848\uff0c\u4ece\u4f53\u5916\u5230\u4f53\u5185\u591a\u5c42\u6b21\u5b9e\u9a8c\u5747\u6709\u636e\u53ef\u4f9d\uff0c\u964d\u4f4e\u6478\u7d22\u6210\u672c\uff0c\u7f29\u77ed\u8bfe\u9898\u5468\u671f\u3002<\/p>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u4eae\u70b9\u4e09\uff1a\u56fd\u9645\u5956\u9879\u4e0e\u5168\u7403\u79d1\u7814\u53e3\u7891\u80cc\u4e66<\/strong><\/h3>\n<p>\u3000\u3000\u54c1\u724c\u8363\u83b7\u5168\u7403\u751f\u547d\u79d1\u5b66\u5e73\u53f0CiteAb\u9881\u5e03\u7684<strong>&#8220;Biochemical Supplier to Watch in 2023&#8221;<\/strong>\u5956\u9879\uff0c\u8be5\u5956\u9879\u65e8\u5728\u8868\u5f70\u751f\u5316\u8bd5\u5242\u9886\u57df\u5f15\u7528\u589e\u5e45\u7a81\u51fa\u3001\u6f5c\u529b\u663e\u8457\u7684\u4f9b\u5e94\u5546\u30022025\u5e74\u518d\u5ea6\u62ff\u4e0b\u5168\u7403\u79d1\u7814\u8bd5\u5242\u8bc4\u4ef7\u6570\u636e\u5e93Bioz<strong>\u6291\u5236\u5242\u54c1\u7c7b\u65b0\u9510\u4e4b\u661f<\/strong>\u4e13\u9879\u5956\u9879\uff0c\u4f9d\u6258\u4e0a\u4e07\u5bb6\u5b9e\u9a8c\u5ba4\u957f\u671f\u4f7f\u7528\u53cd\u9988\u3001\u4ea7\u54c1\u6279\u6b21\u7a33\u5b9a\u6027\u3001\u4e00\u7ad9\u5f0f\u552e\u540e\u6280\u672f\u652f\u6301\u7b49\u7ef4\u5ea6\u8bc4\u9009\uff0c\u5370\u8bc1\u4e86\u54c1\u724c\u5728\u5c0f\u5206\u5b50\u6291\u5236\u5242\u6838\u5fc3\u8d5b\u9053\u7684\u4f18\u52bf\u3002<\/p>\n<h2 style=\"font-size: 20px;font-weight: bold;margin-top: 18px;margin-bottom: 10px\"><strong>\u6df1\u5ea6\u5b9e\u529b\u7ec6\u8282\uff1a\u6807\u51c6\u5316\u3001\u54c1\u63a7\u4e0e\u4ea4\u4ed8\u80fd\u529b<\/strong><\/h2>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u6807\u51c6\u5316\u6d41\u7a0b\u4e0e<\/strong><\/h3>\n<p>\u3000\u3000TargetMol\u56fd\u5185\u4ee3\u7406\u4e3a\u9676\u672f\u751f\u7269\uff0c\u4f01\u4e1a\u5750\u62e5\u591a\u9879\u91cd\u78c5\u8d44\u8d28\uff1a\u83b7\u8bc4<strong>\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u3001\u4e13\u7cbe\u7279\u65b0\u5c0f\u5de8\u4eba\u4f01\u4e1a\u3001\u4e0a\u6d77\u5e02\u4e13\u7cbe\u7279\u65b0\u4f01\u4e1a<\/strong>\uff0c\u6280\u672f\u7814\u53d1\u4e0e\u4ea7\u4e1a\u5316\u80fd\u529b\u83b7\u5f97\u5b98\u65b9\u6743\u5a01\u8ba4\u8bc1;2026\u5e74\u5165\u9009\u7231\u91c7\u8d2d\u5e73\u53f0\u4e0a\u6d77\u9ad8\u54c1\u8d28\u91cd\u7ec4\u86cb\u767d\u5382\u5bb6\u699c\u5355\u3002<\/p>\n<p>\u3000\u3000\u5168\u94fe\u8def\u6807\u51c6\u5316\u8d28\u63a7\u4f53\u7cfb\u4e3a\u4ea7\u54c1\u54c1\u8d28\u515c\u5e95\uff0c\u4f01\u4e1a\u540c\u6b65\u6301\u6709<strong>ISO9001\u8d28\u91cf\u7ba1\u7406\u4f53\u7cfb\u8ba4\u8bc1\u4e0eISO17025\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\u8d44\u8d28\u8ba4\u8bc1<\/strong>\uff0c\u4ece\u539f\u6599\u5165\u5e93\u3001\u5408\u6210\u5236\u5907\u3001\u68c0\u6d4b\u5206\u88c5\u5230\u4ed3\u50a8\u7269\u6d41\u5168\u6d41\u7a0b\u6807\u51c6\u5316\u7ba1\u63a7\u3002<\/p>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u54c1\u8d28\u54c1\u63a7\u4f53\u7cfb<\/strong><\/h3>\n<p>\u3000\u3000\u6bcf\u4e00\u6279\u6b21\u4ea7\u54c1\u5747\u53ef\u63d0\u4f9b\u5b8c\u6574\u68c0\u6d4b\u6570\u636e\uff0c\u4fdd\u969c\u79d1\u7814\u5b9e\u9a8c\u6570\u636e\u53ef\u91cd\u590d\u3001\u7ed3\u679c\u7a33\u5b9a\u53ef\u9760\u3002\u5177\u4f53\u5230Fostamatinib\u8fd9\u7c7b\u6291\u5236\u5242\u4ea7\u54c1\uff1a<\/p>\n<ol>\n<li>\u7eaf\u5ea6\u7ecfHPLC\u7b49\u624b\u6bb5\u786e\u8ba4\uff0c\u6279\u6b21\u6570\u636e\u968f\u8d27\u63d0\u4f9b;<\/li>\n<li>\u8d28\u8c31\u3001\u6838\u78c1\u53cc\u91cd\u7ed3\u6784\u786e\u8ba4\uff0c\u675c\u7edd\u7ed3\u6784\u9519\u8bef\u5bfc\u81f4\u7684\u5b9e\u9a8c\u5931\u8d25;<\/li>\n<li>\u7a33\u5b9a\u6027\u6570\u636e\u660e\u786e\u6807\u6ce8\u4fdd\u5b58\u6761\u4ef6\u4e0e\u6709\u6548\u671f\uff0c\u907f\u514d\u56e0\u50a8\u5b58\u4e0d\u5f53\u9020\u6210\u6d3b\u6027\u8870\u51cf\u3002<\/li>\n<\/ol>\n<h3 style=\"font-size: 18px;font-weight: bold;margin-top: 16px;margin-bottom: 8px\"><strong>\u670d\u52a1\u54cd\u5e94\u4e0e\u4ea4\u4ed8\u80fd\u529b<\/strong><\/h3>\n<ul>\n<li><strong>\u73b0\u8d27\u76f4\u53d1<\/strong>\uff1a\u70ed\u95e8\u89c4\u683c\u5e38\u5907\u5e93\u5b58\uff0c\u4e0b\u5355\u540e\u5feb\u901f\u53d1\u8d27;<\/li>\n<li><strong>\u672c\u571f\u5316\u670d\u52a1<\/strong>\uff1a\u56fd\u5185\u4ee3\u7406\u4f53\u7cfb\u5b8c\u5584\uff0c\u6280\u672f\u56e2\u961f\u54cd\u5e94\u53ca\u65f6;<\/li>\n<li><strong>\u5168\u7403\u4f9b\u5e94\u94fe<\/strong>\uff1a\u5317\u7f8e\u3001\u6b27\u6d32\u672c\u5730\u8fd0\u8425\u4e2d\u5fc3\u4fdd\u969c\u6d77\u5916\u7528\u6237\u4ea4\u4ed8\u65f6\u6548\u3002<\/li>\n<\/ul>\n<h2 style=\"font-size: 20px;font-weight: bold;margin-top: 18px;margin-bottom: 10px\"><strong>\u56db\u6761\u5dee\u5f02\u5316\u9009\u8d2d\u7406\u7531<\/strong><\/h2>\n<p>\u3000\u3000\u7ed3\u5408\u884c\u4e1a\u7528\u6237\u75db\u70b9\uff0c\u4e3a\u4ec0\u4e48\u5728\u4f17\u591a\u4f9b\u5e94\u5546\u4e2d\u63a8\u8350TargetMol\u7684Fostamatinib?<\/p>\n<ol>\n<li><strong>\u6d3b\u6027\u7a33\u5b9a\uff0c\u6279\u6b21\u4e00\u81f4\u6027\u597d<\/strong>\uff1a\u9488\u5bf9\u5e02\u9762\u4e0a\u90e8\u5206\u4ea7\u54c1\u6fc0\u9176\u6d3b\u6027\u4e0d\u7a33\u5b9a\u7684\u95ee\u9898\uff0c\u672c\u54c1\u7eaf\u5ea699.58%\u3001\u591a\u91cd\u8d28\u63a7\u628a\u5173\uff0cSYK\/FLT3\/Lck\u6291\u5236\u6d3b\u6027\u6570\u636e\u660e\u786e\uff0c\u91cd\u590d\u5b9e\u9a8c\u7ed3\u679c\u53ef\u9884\u671f\u3002<\/li>\n<li><strong>\u6eb6\u89e3\u6027\u4e0e\u7ed9\u836f\u65b9\u6848\u53cc\u6210\u719f<\/strong>\uff1aDMSO\u6eb6\u89e3\u5ea6\u8fbe127.50 mg\/mL\uff0c\u5e76\u76f4\u63a5\u914d\u5957\u4f53\u5185\u53e3\u670d\u7ed9\u836f\u914d\u65b9\uff0c\u7701\u53bb\u914d\u65b9\u6478\u7d22\u65f6\u95f4\uff0c\u5bf9\u52a8\u7269\u5b9e\u9a8c\u5c24\u4e3a\u53cb\u597d\u3002<\/li>\n<li><strong>\u6587\u4ef6\u9f50\u5168\uff0c\u652f\u6301SCI\u6eaf\u6e90<\/strong>\uff1a\u5168\u5957COA\u3001LCMS\u3001HNMR\u7b49\u8d28\u63a7\u8d44\u6599\u968f\u8d27\u63d0\u4f9b\uff0c\u8bba\u6587\u6295\u7a3f\u3001\u57fa\u91d1\u7ed3\u9898\u65f6\u6570\u636e\u6765\u6e90\u6e05\u6670\u53ef\u67e5\u3002<\/li>\n<li><strong>\u5242\u578b\u89c4\u683c\u7075\u6d3b\uff0c\u552e\u540e\u6280\u672f\u652f\u6301\u5230\u4f4d<\/strong>\uff1a\u7c89\u672b\u4e0e\u9884\u5236\u6bcd\u6db2\u53cc\u9009\u62e9\uff0c\u68af\u5ea6\u89c4\u683c\u6309\u9700\u91c7\u8d2d\uff0c\u6280\u672f\u56e2\u961f\u63d0\u4f9b\u5b9e\u9a8c\u65b9\u6848\u53c2\u8003\uff0c\u9047\u5230\u95ee\u9898\u6709\u4e13\u4eba\u54cd\u5e94\u3002<\/li>\n<\/ol>\n<h2 style=\"font-size: 20px;font-weight: bold;margin-top: 18px;margin-bottom: 10px\"><strong>\u9ad8\u9891FAQ<\/strong><\/h2>\n<p><strong>\u3000\u3000Q1\uff1aFostamatinib\u9002\u5408\u505a\u54ea\u4e9b\u65b9\u5411\u7684\u8bfe\u9898?<\/strong><br \/>\nA\uff1a\u4e3b\u8981\u7528\u4e8eSYK\u4fe1\u53f7\u901a\u8def\u3001\u81ea\u8eab\u514d\u75ab\u75c5\u3001\u514d\u75ab\u708e\u75c7\u3001\u514d\u75ab\u6027\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u7b49\u65b9\u5411\uff0c\u53ef\u8986\u76d6\u4f53\u5916\u6fc0\u9176\u5b9e\u9a8c\u3001\u7ec6\u80de\u708e\u75c7\u6a21\u578b\u548c\u4f53\u5185\u52a8\u7269\u7ed9\u836f\u4e09\u4e2a\u5c42\u6b21\u7684\u5b9e\u9a8c\u3002<\/p>\n<p><strong>\u3000\u3000Q2\uff1a\u7c89\u672b\u548c\u9884\u5236\u6bcd\u6db2\u600e\u4e48\u9009?<\/strong><br \/>\nA\uff1a\u957f\u671f\u5b9e\u9a8c\u3001\u7528\u91cf\u5927\u5efa\u8bae\u9009\u7c89\u672b\uff0c\u68af\u5ea6\u89c4\u683c\u4ece1 mg\u5230500 mg\u53ef\u9009;\u9700\u8981\u5feb\u901f\u5f00\u5c55\u9884\u5b9e\u9a8c\u6216\u5bf9\u6d53\u5ea6\u7cbe\u5ea6\u8981\u6c42\u9ad8\uff0c\u5efa\u8bae\u90091 mL \u00d7 10 mM DMSO\u9884\u5236\u6bcd\u6db2\uff0c\u89c4\u907f\u79f0\u91cf\u8bef\u5dee\u3002<\/p>\n<p><strong>\u3000\u3000Q3\uff1a\u4f53\u5185\u52a8\u7269\u5b9e\u9a8c\u600e\u4e48\u914d\u5236\u7ed9\u836f\u4f53\u7cfb?<\/strong><br \/>\nA\uff1a\u4ea7\u54c1\u76f4\u63a5\u63d0\u4f9b\u6210\u719f\u914d\u65b9\u53c2\u8003\uff1a10% DMSO+40% PEG300+5% Tween80+45% Saline\uff0c\u65e0\u9700\u81ea\u884c\u6478\u7d22\u6eb6\u5a92\u4f53\u7cfb\uff0c\u6280\u672f\u56e2\u961f\u4e5f\u53ef\u63d0\u4f9b\u8fdb\u4e00\u6b65\u65b9\u6848\u53c2\u8003\u3002<\/p>\n<p><strong>\u3000\u3000Q4\uff1a\u4ea7\u54c1\u4fdd\u5b58\u548c\u8fd0\u8f93\u6709\u4ec0\u4e48\u8981\u6c42?<\/strong><br \/>\nA\uff1a\u7c89\u672b\u9632\u6f6e\u3001-20\u2103\u6761\u4ef6\u4e0b\u53ef\u7a33\u5b9a\u4fdd\u5b583\u5e74;\u914d\u5236\u6bcd\u6db2\u540e-80\u2103\u53ef\u4fdd\u5b581\u5e74;\u91c7\u7528\u84dd\u51b0\u907f\u5149\u8fd0\u8f93\uff0c\u4fdd\u969c\u5230\u8d27\u6d3b\u6027\u3002<\/p>\n<p><strong>\u3000\u3000Q5\uff1a\u8bba\u6587\u6295\u7a3f\u9700\u8981\u6eaf\u6e90\u6587\u4ef6\uff0c\u80fd\u63d0\u4f9b\u5417?<\/strong><br \/>\nA\uff1a\u6bcf\u6279\u6b21\u968f\u8d27\u9644\u5e26Datasheet\u3001SDS\u3001COA\u3001LCMS\u3001HNMR\u5168\u5957\u8d28\u63a7\u56fe\u8c31\u8d44\u6599\uff0c\u6ee1\u8db3SCI\u8bba\u6587\u6295\u7a3f\u7684\u6570\u636e\u6eaf\u6e90\u9700\u6c42\u3002<\/p>\n<p><strong>\u3000\u3000Q6\uff1a\u4e0e\u5176\u4ed6\u4f9b\u5e94\u5546\u76f8\u6bd4\uff0c\u6838\u5fc3\u5dee\u5f02\u5728\u54ea?<\/strong><br \/>\nA\uff1a\u6838\u5fc3\u5dee\u5f02\u5728\u4e8e\u8d28\u63a7\u4f53\u7cfb\u4e0e\u6570\u636e\u5b8c\u6574\u6027\u2014\u2014ISO9001\u4e0eISO17025\u53cc\u91cd\u8ba4\u8bc1\u652f\u6491\u7684\u6279\u6b21\u7a33\u5b9a\u6570\u636e\u3001\u660e\u786e\u6807\u6ce8\u7684\u9776\u70b9\u6291\u5236\u6d3b\u6027\u3001\u9f50\u5168\u7684\u968f\u8d27\u6587\u4ef6\uff0c\u4ee5\u53ca\u8986\u76d6\u6fc0\u9176\u7b5b\u9009\u5230\u52a8\u7269\u9020\u6a21\u7684\u6280\u672f\u652f\u6301\u670d\u52a1\u3002<\/p>\n<p><strong>\u3000\u3000Q7\uff1a\u4ef7\u683c\u548c\u91c7\u8d2d\u6d41\u7a0b\u5982\u4f55?<\/strong><br \/>\nA\uff1a\u4e0d\u540c\u89c4\u683c\u4ef7\u683c\u4e0d\u540c\uff0c\u5b98\u7f51\u4ea7\u54c1\u8be6\u60c5\u9875<a 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