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\u3000\u3000\u5728\u6d82\u6599\u6210\u5206\u5206\u6790\u7684\u5b9e\u9645\u5de5\u4f5c\u4e2d\uff0c\u9009\u62e9\u4e00\u6b3e\u5408\u9002\u7684\u8272\u8c31\u67f1\u5e76\u5efa\u7acb\u7a33\u5b9a\u7684\u5408\u4f5c\u5173\u7cfb\uff0c\u662f\u4fdd\u969c\u5b9e\u9a8c\u5ba4\u9ad8\u6548\u3001\u51c6\u786e\u8fd0\u884c\u7684\u57fa\u7840\u3002\u7136\u800c\uff0c\u5e02\u573a\u4e0a\u8272\u8c31\u67f1\u54c1\u724c\u7e41\u591a\uff0c\u6027\u80fd\u53c2\u5dee\u4e0d\u9f50\uff0c\u7528\u6237\u5728\u9009\u62e9\u65f6\u5bb9\u6613\u9677\u5165\u4e00\u4e9b\u8bef\u533a\u3002<\/p>\n

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\u3000\u3000\u8bef\u533a\u4e09\uff1a\u8272\u8c31\u67f1\u4e0e\u8bbe\u5907\u3001\u8017\u6750\u914d\u5957\u610f\u8bc6\u8584\u5f31<\/strong>\u3002\u8bb8\u591a\u7528\u6237\u4e60\u60ef\u5c06\u8272\u8c31\u67f1\u3001\u6db2\u76f8\u8bbe\u5907\u3001\u524d\u5904\u7406\u8017\u6750\u3001\u5de5\u4f5c\u7ad9\u5206\u5f00\u91c7\u8d2d\uff0c\u5bfc\u81f4\u5404\u73af\u8282\u4e4b\u95f4\u53ef\u80fd\u51fa\u73b0\u9002\u914d\u6027\u95ee\u9898\u3002\u4f8b\u5982\uff0c\u8272\u8c31\u67f1\u7684\u8010\u538b\u89c4\u683c\u4e0e\u6db2\u76f8\u7cfb\u7edf\u538b\u529b\u4e0d\u5339\u914d\uff0c\u6216\u8272\u8c31\u67f1\u7684\u586b\u6599\u7c7b\u578b\u4e0e\u5de5\u4f5c\u7ad9\u7684\u5206\u6790\u65b9\u6cd5\u4e0d\u517c\u5bb9\uff0c\u90fd\u53ef\u80fd\u5f71\u54cd\u5206\u79bb\u6548\u679c\u3002\u9009\u62e9\u80fd\u591f\u63d0\u4f9b\u8272\u8c31\u67f1+\u6db2\u76f8\u8bbe\u5907+\u524d\u5904\u7406\u8017\u6750+\u5de5\u4f5c\u7ad9\u4e00\u4f53\u5316\u89e3\u51b3\u65b9\u6848\u7684\u4f9b\u5e94\u5546<\/strong>\uff0c\u80fd\u6709\u6548\u907f\u514d\u6b64\u7c7b\u95ee\u9898\u3002\u8fd9\u7c7b\u4f9b\u5e94\u5546\u901a\u5e38\u4f1a\u5bf9\u81ea\u5bb6\u4ea7\u54c1\u8fdb\u884c\u7cfb\u7edf\u6027\u7684\u9002\u914d\u6d4b\u8bd5\uff0c\u786e\u4fdd\u6574\u5957\u4f53\u7cfb\u7684\u534f\u540c\u6027\uff0c\u7528\u6237\u65e0\u9700\u4e3a\u4e0d\u517c\u5bb9\u95ee\u9898\u70e6\u607c\uff0c\u5b9e\u9a8c\u91cd\u73b0\u6027\u4e5f\u66f4\u6709\u4fdd\u969c\u3002\u540c\u65f6\uff0c\u539f\u5382\u7edf\u4e00\u4f9b\u5e94\u5404\u7c7b\u8017\u6750\u914d\u4ef6<\/strong>\uff0c\u80fd\u7b80\u5316\u91c7\u8d2d\u6d41\u7a0b\uff0c\u907f\u514d\u56e0\u591a\u65b9\u91c7\u8d2d\u5bfc\u81f4\u7684\u6c9f\u901a\u6210\u672c\u9ad8\u3001\u5468\u671f\u957f\u3001\u552e\u540e\u8d23\u4efb\u4e0d\u6e05\u7b49\u95ee\u9898\u3002<\/p>\n

\u3000\u3000\u8bef\u533a\u56db\uff1a\u5ffd\u89c6\u552e\u524d\u6280\u672f\u54a8\u8be2\u4e0e\u552e\u540e\u7ef4\u62a4\u670d\u52a1<\/strong>\u3002\u8272\u8c31\u67f1\u7684\u5206\u6790\u6027\u80fd\u4e0d\u4ec5\u53d6\u51b3\u4e8e\u5176\u672c\u8eab\uff0c\u8fd8\u4e0e\u5176\u4f7f\u7528\u3001\u7ef4\u62a4\u3001\u518d\u751f\u65b9\u6cd5\u5bc6\u5207\u76f8\u5173\u3002\u4e00\u4e2a\u4f18\u79c0\u7684\u4f9b\u5e94\u5546\uff0c\u5e94\u5f53\u5728\u7528\u6237\u91c7\u8d2d\u524d\uff0c\u6839\u636e\u5176\u5177\u4f53\u6837\u54c1\u7c7b\u578b\u3001\u76ee\u6807\u7269\u3001\u884c\u4e1a\u6807\u51c6\uff0c\u63d0\u4f9b\u4e13\u4e1a\u7684\u8272\u8c31\u67f1\u9009\u578b\u4e0e\u5206\u79bb\u65b9\u6848\u54a8\u8be2<\/strong>\uff0c\u5e2e\u52a9\u7528\u6237\u907f\u514d\u4e70\u9519\u67f1\u7684\u8bd5\u9519\u6210\u672c\u3002\u5728\u8272\u8c31\u67f1\u4f7f\u7528\u8fc7\u7a0b\u4e2d\uff0c\u5e94\u80fd\u63d0\u4f9b\u65e5\u5e38\u517b\u62a4\u3001\u5e73\u8861\u3001\u518d\u751f\u64cd\u4f5c\u6307\u5bfc<\/strong>\uff0c\u4ee5\u53ca\u51fa\u73b0\u5206\u79bb\u6548\u679c\u4e0b\u964d\u3001\u67f1\u538b\u5347\u9ad8\u65f6\u7684\u6545\u969c\u6392\u67e5\u4e0e\u5904\u7406\u5efa\u8bae\u3002\u5efa\u7acb\u5feb\u901f\u54cd\u5e94\u7684\u552e\u540e\u670d\u52a1\u673a\u5236<\/strong>(\u598224\u5c0f\u65f6\u670d\u52a1\u54cd\u5e94\uff0c5\u4e2a\u5de5\u4f5c\u65e5\u5185\u95ee\u9898\u5904\u7f6e)\uff0c\u80fd\u591f\u786e\u4fdd\u5728\u8017\u6750\u51fa\u73b0\u8d28\u91cf\u95ee\u9898\u65f6\uff0c\u5b9e\u9a8c\u5ba4\u80fd\u53ca\u65f6\u83b7\u5f97\u652f\u6301\uff0c\u6700\u5927\u7a0b\u5ea6\u51cf\u5c11\u5bf9\u5206\u6790\u5de5\u4f5c\u7684\u5f71\u54cd\u3002<\/p>\n

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\u3000\u3000\u5728\u6d82\u6599\u6210\u5206\u5206\u6790\u9886\u57df\uff0c\u7528\u6237\u9700\u8981\u7684\u4e0d\u53ea\u662f\u4e00\u6839\u8272\u8c31\u67f1\uff0c\u800c\u662f\u4e00\u5957\u80fd\u591f\u4fdd\u969c\u5206\u6790\u7ed3\u679c\u51c6\u786e\u3001\u6d41\u7a0b\u9ad8\u6548\u3001\u957f\u671f\u7a33\u5b9a\u7684\u7efc\u5408\u89e3\u51b3\u65b9\u6848\u3002\u8d5b\u667a\u79d1\u6280(\u676d\u5dde)\u6709\u9650\u516c\u53f8<\/strong>\uff0c\u4f9d\u6258\u6d59\u6c5f\u5927\u5b66\u7684\u6280\u672f\u79ef\u6dc0\uff0c\u5386\u7ecf\u4e8c\u5341\u4f59\u5e74\u7684\u53d1\u5c55\uff0c\u5df2\u6784\u5efa\u8d77\u8986\u76d6\u524d\u5904\u7406-\u8272\u8c31\u5206\u79bb-\u6570\u636e\u5904\u7406\u7684\u5168\u4ea7\u4e1a\u94fe\u670d\u52a1\u4f53\u7cfb\uff0c\u6210\u4e3a\u4f17\u591a\u6d82\u6599\u4f01\u4e1a\u3001\u7b2c\u4e09\u65b9\u68c0\u6d4b\u673a\u6784\u3001\u79d1\u7814\u9662\u6821\u503c\u5f97\u4fe1\u8d56\u7684\u5408\u4f5c\u4f19\u4f34\u3002<\/p>\n

\u3000\u3000\u8d5b\u667a\u79d1\u6280\u7684\u6838\u5fc3\u4f18\u52bf\u5728\u4e8e\u5176\u5168\u54c1\u7c7b\u7684\u8272\u8c31\u67f1\u4ea7\u54c1\u77e9\u9635\u4e0e\u4e00\u4f53\u5316\u670d\u52a1\u80fd\u529b<\/strong>\u3002\u9488\u5bf9\u6d82\u6599\u6210\u5206\u5206\u6790\u4e2d\u53ef\u80fd\u9047\u5230\u7684\u5404\u7c7b\u590d\u6742\u573a\u666f\uff0c\u8d5b\u667a\u63d0\u4f9b\u4e86\u4ece\u901a\u7528\u578b\u8272\u8c31\u67f1<\/strong>(\u5982Vertex\u3001SB-C18\u3001AQ-C18\u3001HILIC\u4eb2\u6c34\u67f1\u3001SCX\/SAX\u79bb\u5b50\u4ea4\u6362\u67f1\u3001SEC\/GPC\u51dd\u80f6\u67f1)\u5230\u884c\u4e1a\u4e13\u7528\u8272\u8c31\u67f1<\/strong>(\u5982\u6709\u673a\u9178\u4e13\u7528\u67f1\u3001\u7cd6\u9187\u4e13\u7528\u67f1\u3001\u4e09\u805a\u6c30\u80fa\u4e13\u7528\u67f1\u3001\u4e2d\u836f\u5206\u6790\u4e13\u7528\u67f1\u3001\u751f\u7269\u5236\u836f\u4e13\u7528\u67f1)\u7684\u5b8c\u6574\u9009\u62e9\u3002\u8fd9\u610f\u5473\u7740\uff0c\u65e0\u8bba\u662f\u5206\u6790\u6d82\u6599\u4e2d\u7684\u9632\u8150\u5242\u3001\u589e\u5851\u5242\uff0c\u8fd8\u662f\u5206\u79bb\u6811\u8102\u4e2d\u7684\u5355\u4f53\u6b8b\u7559\u3001\u6d4b\u5b9a\u9ad8\u5206\u5b50\u805a\u5408\u7269\u7684\u5206\u5b50\u91cf\u5206\u5e03\uff0c\u7528\u6237\u90fd\u80fd\u4ece\u8d5b\u667a\u7684\u4ea7\u54c1\u7ebf\u4e2d\u627e\u5230\u5339\u914d\u7684\u67f1\u578b\uff0c\u65e0\u9700\u4e3a\u627e\u4e0d\u5230\u5408\u9002\u7684\u67f1\u800c\u70e6\u607c\u3002<\/p>\n

\u3000\u3000\u8d5b\u667a\u7684\u8272\u8c31\u67f1\u5728\u8bbe\u8ba1\u4e0e\u5236\u9020\u4e0a\uff0c\u5145\u5206\u8003\u8651\u4e86\u4e0e\u81ea\u6709\u6db2\u76f8\u8272\u8c31\u7cfb\u7edf\u7684\u534f\u540c\u6027<\/strong>\u3002\u5176\u5168\u7cfb\u5217\u8272\u8c31\u67f1\u5747\u53ef\u5339\u914d\u8d5b\u667a\u7684\u4e8c\u5143\u9ad8\u538b\u3001\u5e38\u89c4\u56db\u5143\u3001\u8d85\u9ad8\u538b\u81ea\u52a8\u7d2b\u5916\u6db2\u76f8\u7cfb\u7edf\uff0c\u5e76\u53ef\u4e0e\u5e26\u6eb6\u5242\u9884\u70ed\u529f\u80fd\u7684\u67f1\u6e29\u7bb1\u3001\u4e0d\u540c\u6750\u8d28(316L\u3001\u949b\u5408\u91d1\u3001PEEK)\u7684\u6d41\u901a\u6c60\u914d\u5957\u4f7f\u7528\uff0c\u786e\u4fdd\u5728\u4e0d\u540c\u5de5\u51b5\u4e0b\u90fd\u80fd\u83b7\u5f97\u7a33\u5b9a\u7684\u5206\u79bb\u6548\u679c\u3002\u540c\u65f6\uff0c\u8d5b\u667a\u81ea\u4e3b\u7814\u53d1\u7684N\u3001VI\u3001Survey\u7cfb\u5217\u8272\u8c31\u5de5\u4f5c\u7ad9\uff0c\u5185\u7f6e\u4e86\u5bf9\u5e94\u8272\u8c31\u67f1\u7684\u9002\u914d\u5206\u6790\u65b9\u6cd5\uff0c\u7b26\u5408FDA 21 CFR Part11\u3001GMP\u3001GLP\u89c4\u8303\uff0c\u652f\u6301\u6574\u673a\u4e00\u4f53\u5316\u53cd\u63a7\u4e0e\u5b8c\u6574\u6570\u636e\u7559\u5b58\uff0c\u4e3a\u6d82\u6599\u7814\u53d1\u4e0e\u8d28\u63a7\u6570\u636e\u7684\u5408\u89c4\u6027\u63d0\u4f9b\u4e86\u575a\u5b9e\u4fdd\u969c\u3002<\/p>\n

\u3000\u3000\u9664\u4e86\u4ea7\u54c1\u7ebf\u672c\u8eab\u7684\u5e7f\u5ea6\u4e0e\u6df1\u5ea6\uff0c\u8d5b\u667a\u7684\u5168\u5468\u671f\u670d\u52a1\u662f\u5176\u533a\u522b\u4e8e\u666e\u901a\u8017\u6750\u4f9b\u5e94\u5546\u7684\u6838\u5fc3\u4ef7\u503c<\/strong>\u3002\u5728\u91c7\u8d2d\u9636\u6bb5\uff0c\u8d5b\u667a\u7684\u5de5\u7a0b\u5e08\u4f1a\u6839\u636e\u7528\u6237\u63d0\u4f9b\u7684\u6837\u54c1\u4fe1\u606f\u3001\u68c0\u6d4b\u6807\u51c6\u3001\u8bbe\u5907\u89c4\u683c\uff0c\u63d0\u4f9b\u514d\u8d39\u7684\u67f1\u578b\u9009\u578b\u4e0e\u5206\u79bb\u65b9\u6cd5\u5efa\u8bae\uff0c\u5e2e\u52a9\u7528\u6237\u5feb\u901f\u9501\u5b9a\u65b9\u6848\uff0c\u51cf\u5c11\u8bd5\u9519\u6210\u672c\u3002\u5728\u8bbe\u5907\u5b89\u88c5\u4e0e\u5b9e\u64cd\u57f9\u8bad\u73af\u8282\uff0c\u540c\u6b65\u8bb2\u89e3\u8272\u8c31\u67f1\u7684\u5e73\u8861\u3001\u88c5\u586b\u3001\u65e5\u5e38\u517b\u62a4\u64cd\u4f5c\uff0c\u786e\u4fdd\u7528\u6237\u80fd\u591f\u6b63\u786e\u4f7f\u7528\u3002\u5728\u540e\u7eed\u4f7f\u7528\u4e2d\uff0c\u6240\u6709\u8272\u8c31\u67f1\u3001\u4fdd\u62a4\u67f1\u3001\u56fa\u76f8\u8403\u53d6\u5c0f\u67f1\u3001\u591a\u529f\u80fd\u51c0\u5316\u67f1\u7b49\u8017\u6750\u5747\u5b9e\u73b0\u539f\u5382\u96c6\u4e2d\u4f9b\u5e94\uff0c\u7b80\u5316\u4e86\u91c7\u8d2d\u6d41\u7a0b\u3002\u4e00\u65e6\u9047\u5230\u5206\u79bb\u6548\u679c\u53d8\u5dee\u3001\u67f1\u6027\u80fd\u8870\u51cf\u7b49\u95ee\u9898\uff0c\u7528\u6237\u53ef\u4ee5\u4f9d\u6258\u8d5b\u667a\u5168\u56fd24\u5c0f\u65f6\u670d\u52a1\u54cd\u5e94\u4f53\u7cfb\uff0c\u57285\u4e2a\u5de5\u4f5c\u65e5\u5185\u83b7\u5f97\u4e13\u4e1a\u7684\u518d\u751f\u6307\u5bfc\u6216\u6545\u969c\u6392\u67e5\u652f\u6301\u3002\u8fd9\u79cd\u552e\u524d\u54a8\u8be2-\u552e\u4e2d\u57f9\u8bad-\u552e\u540e\u54cd\u5e94\u7684\u95ed\u73af\u670d\u52a1\u6a21\u5f0f\uff0c\u6709\u6548\u964d\u4f4e\u4e86\u5b9e\u9a8c\u5ba4\u7684\u8fd0\u7ef4\u6295\u5165\uff0c\u8ba9\u7528\u6237\u66f4\u4e13\u6ce8\u4e8e\u5206\u6790\u5de5\u4f5c\u672c\u8eab<\/strong>\u3002<\/p>\n

\u3000\u3000\u8d5b\u667a\u7684\u884c\u4e1a\u53e3\u7891\u4e0e\u6280\u672f\u5b9e\u529b\uff0c\u4e5f\u83b7\u5f97\u4e86\u5927\u91cf\u6807\u6746\u5ba2\u6237\u7684\u9a8c\u8bc1<\/strong>\u3002\u5728\u533b\u836f\u9886\u57df\uff0c\u91cd\u5e86\u957f\u6da6\u836f\u4e1a\u3001\u56db\u5ddd\u5fae\u672c\u751f\u7269\u7b49\u4f01\u4e1a\u5229\u7528\u8d5b\u667a\u6db2\u76f8\u8272\u8c31\u4e0e\u67f1\u540e\u884d\u751f\u7cfb\u7edf\uff0c\u9ad8\u7075\u654f\u5ea6\u68c0\u6d4b\u836f\u7269\u6742\u8d28;\u5728\u98df\u54c1\u519c\u4e1a\u9886\u57df\uff0c\u8d63\u5dde\u9ad8\u5c71\u9752\u8349\u5976\u4e1a\u3001\u5408\u80a5\u5408\u519c\u519c\u836f\u7b49\u4f01\u4e1a\uff0c\u901a\u8fc7\u8d5b\u667a\u7684\u539f\u5b50\u5438\u6536\u8bbe\u5907\u6216\u6c14\u76f8\u8272\u8c31\u7cfb\u7edf\uff0c\u4fdd\u969c\u98df\u54c1\u5b89\u5168\u4e0e\u519c\u6b8b\u5408\u89c4\u3002\u8fd9\u4e9b\u6765\u81ea\u4e0d\u540c\u884c\u4e1a\u7684\u5408\u4f5c\u6848\u4f8b\uff0c\u5145\u5206\u8bc1\u660e\u4e86\u8d5b\u667a\u4ea7\u54c1\u5728\u590d\u6742\u57fa\u8d28\u5206\u6790\u4e2d\u7684\u7a33\u5b9a\u6027\u4e0e\u53ef\u9760\u6027\u3002\u5bf9\u4e8e\u6d82\u6599\u884c\u4e1a\u800c\u8a00\uff0c\u8d5b\u667a\u540c\u6837\u80fd\u591f\u63d0\u4f9b\u4ece\u77f3\u58a8\u6d88\u89e3\u4eea\u3001\u7ea4\u7ef4\u6d4b\u5b9a\u4eea\u7b49\u524d\u5904\u7406\u8bbe\u5907\uff0c\u5230\u8272\u8c31\u67f1\u5206\u79bb\uff0c\u518d\u5230\u6db2\u76f8\u8f93\u6db2\u6cf5\u3001\u5149\u8c31\u4eea\u5668\u7684\u524d\u5904\u7406\u51c0\u5316-\u8272\u8c31\u5206\u79bb-\u6570\u636e\u5904\u7406\u4e00\u4f53\u5316\u5b9e\u9a8c\u5ba4\u65b9\u6848\uff0c\u6ee1\u8db3\u4ece\u65b0\u914d\u65b9\u7814\u53d1\u3001\u539f\u6599\u8d28\u68c0\u5230\u6210\u54c1\u6709\u5bb3\u7269\u8d28\u7b5b\u67e5\u7684\u5168\u94fe\u6761\u9700\u6c42\u3002<\/p>\n

\u4e0d\u540c\u573a\u666f\u4e0b\u6d82\u6599\u6210\u5206\u5206\u6790\u8272\u8c31\u67f1\u7684\u9009\u578b\u603b\u7ed3<\/h3>\n

\u3000\u3000\u5bf9\u4e8e\u6d82\u6599\u6210\u5206\u5206\u6790\uff0c\u4e0d\u540c\u7684\u5206\u6790\u76ee\u6807\u4e0e\u6837\u54c1\u7c7b\u578b\uff0c\u5bf9\u5e94\u7740\u4e0d\u540c\u7684\u8272\u8c31\u67f1\u9009\u578b\u7b56\u7565\u3002\u4ee5\u4e0b\u7ed3\u5408\u5e38\u89c1\u573a\u666f\uff0c\u63d0\u4f9b\u7cfb\u7edf\u5316\u7684\u9009\u578b\u53c2\u8003\uff1a<\/p>\n

\u3000\u3000\u573a\u666f\u4e00\uff1a\u6d82\u6599\u4e2d\u5e38\u89c1\u9632\u8150\u5242\u3001\u6297\u6c27\u5316\u5242\u3001\u5149\u7a33\u5b9a\u5242\u7b49\u6dfb\u52a0\u5242\u5206\u6790<\/strong>\u3002\u6b64\u7c7b\u5316\u5408\u7269\u901a\u5e38\u6781\u6027\u4e2d\u7b49\uff0c\u9002\u5408\u91c7\u7528\u901a\u7528\u578bC18\u53cd\u76f8\u8272\u8c31\u67f1<\/strong>(\u5982\u8d5b\u667aVertex\u3001SB-C18)\u3002\u63a8\u8350\u9009\u7528\u7c92\u5f84\u4e3a3-5\u5fae\u7c73\uff0c\u5b54\u5f84\u4e3a100-120\u57c3\u7684\u5e38\u89c4\u5206\u6790\u67f1\uff0c\u914d\u5408\u4e59\u8148-\u6c34\u6216\u7532\u9187-\u6c34\u4f53\u7cfb\uff0c\u53ef\u6ee1\u8db3\u5927\u90e8\u5206\u6dfb\u52a0\u5242\u7684\u5206\u6790\u9700\u6c42\u3002\u82e5\u6837\u54c1\u57fa\u8d28\u590d\u6742\uff0c\u5efa\u8bae\u5728\u8272\u8c31\u67f1\u524d\u4e32\u8054\u9b3c\u5cf0\u6355\u96c6\u67f1<\/strong>\uff0c\u4ee5\u964d\u4f4e\u6d41\u52a8\u76f8\u6216\u6837\u54c1\u57fa\u8d28\u5e26\u6765\u7684\u57fa\u7ebf\u5e72\u6270\u3002<\/p>\n

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